Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | BIOCARTA_KERATINOCYTE DIFFERENTIATION |
| Enrichment Score (ES) | -0.6543342 |
| Normalized Enrichment Score (NES) | -1.8548694 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.046757035 |
| FWER p-Value | 0.131 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | EGFR | 1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at | 951 | 1.215 | -0.0115 | No | ||
| 2 | MAPK13 | 1448871_at | 1070 | 1.134 | 0.0129 | No | ||
| 3 | IKBKB | 1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at | 1312 | 0.982 | 0.0277 | No | ||
| 4 | NFKBIA | 1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at | 2151 | 0.670 | 0.0071 | No | ||
| 5 | GRB2 | 1418508_a_at 1449111_a_at | 3682 | 0.394 | -0.0525 | No | ||
| 6 | CEBPA | 1418982_at | 4249 | 0.342 | -0.0693 | No | ||
| 7 | SHC1 | 1422853_at 1422854_at | 5156 | 0.282 | -0.1033 | No | ||
| 8 | TNF | 1419607_at | 6279 | 0.215 | -0.1489 | No | ||
| 9 | MAPK14 | 1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at | 6350 | 0.212 | -0.1465 | No | ||
| 10 | MAP2K1 | 1416351_at | 6588 | 0.201 | -0.1521 | No | ||
| 11 | PPP2R5D | 1450560_a_at | 6991 | 0.183 | -0.1657 | No | ||
| 12 | CHUK | 1417091_at 1428210_s_at 1451383_a_at | 7004 | 0.182 | -0.1614 | No | ||
| 13 | HOXA7 | 1449499_at | 7352 | 0.166 | -0.1729 | No | ||
| 14 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 8428 | 0.124 | -0.2188 | No | ||
| 15 | PRKCA | 1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at | 8674 | 0.116 | -0.2269 | No | ||
| 16 | EGF | 1418093_a_at | 9401 | 0.090 | -0.2577 | No | ||
| 17 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 10594 | 0.051 | -0.3108 | No | ||
| 18 | PRKCD | 1422847_a_at 1442256_at | 10785 | 0.044 | -0.3184 | No | ||
| 19 | FASLG | 1418803_a_at 1449235_at | 10804 | 0.043 | -0.3180 | No | ||
| 20 | RIPK1 | 1419508_at 1439273_at 1449485_at | 12198 | -0.004 | -0.3816 | No | ||
| 21 | HRAS | 1422407_s_at 1424132_at | 12396 | -0.011 | -0.3903 | No | ||
| 22 | PRKCH | 1422079_at 1434248_at | 13942 | -0.070 | -0.4591 | No | ||
| 23 | MAP2K3 | 1425456_a_at 1451714_a_at | 14805 | -0.108 | -0.4956 | No | ||
| 24 | SOS1 | 1421884_at 1421885_at 1421886_at | 15287 | -0.131 | -0.5141 | No | ||
| 25 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 16000 | -0.170 | -0.5422 | No | ||
| 26 | FOS | 1423100_at | 16233 | -0.185 | -0.5480 | No | ||
| 27 | BIRC3 | 1421392_a_at 1425223_at | 16666 | -0.214 | -0.5621 | No | ||
| 28 | DAXX | 1419026_at | 16816 | -0.225 | -0.5630 | No | ||
| 29 | IKBKG | 1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at | 16819 | -0.225 | -0.5571 | No | ||
| 30 | PRKCE | 1437860_at 1437861_s_at 1442609_at 1444649_at 1449956_at 1452878_at | 17102 | -0.248 | -0.5635 | No | ||
| 31 | JUN | 1417409_at 1448694_at | 17249 | -0.260 | -0.5633 | No | ||
| 32 | PRKCQ | 1426044_a_at | 17459 | -0.279 | -0.5656 | No | ||
| 33 | BIRC2 | 1418854_at | 19403 | -0.591 | -0.6388 | Yes | ||
| 34 | RELA | 1419536_a_at | 19605 | -0.642 | -0.6311 | Yes | ||
| 35 | MAPK3 | 1427060_at | 19743 | -0.679 | -0.6195 | Yes | ||
| 36 | PLAT | 1415806_at 1458553_at | 19794 | -0.693 | -0.6035 | Yes | ||
| 37 | FAS | 1460251_at | 19987 | -0.757 | -0.5924 | Yes | ||
| 38 | MAP4K4 | 1422615_at 1440609_at 1448050_s_at 1459912_at | 20107 | -0.798 | -0.5769 | Yes | ||
| 39 | TRAF2 | 1451233_at | 20231 | -0.852 | -0.5601 | Yes | ||
| 40 | RAF1 | 1416078_s_at 1425419_a_at | 20370 | -0.914 | -0.5424 | Yes | ||
| 41 | TRAF1 | 1423602_at 1445452_at | 20906 | -1.270 | -0.5334 | Yes | ||
| 42 | MAP3K1 | 1424850_at | 20926 | -1.284 | -0.5005 | Yes | ||
| 43 | MAP2K4 | 1426233_at 1442679_at 1451982_at | 21011 | -1.366 | -0.4684 | Yes | ||
| 44 | MAP2K6 | 1426850_a_at 1459292_at | 21374 | -1.800 | -0.4377 | Yes | ||
| 45 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 21451 | -1.949 | -0.3899 | Yes | ||
| 46 | TNFRSF1A | 1417291_at | 21491 | -2.031 | -0.3382 | Yes | ||
| 47 | ETS1 | 1422027_a_at 1422028_a_at 1426725_s_at 1452163_at | 21702 | -2.610 | -0.2792 | Yes | ||
| 48 | SP1 | 1418180_at 1448994_at 1454852_at | 21713 | -2.651 | -0.2099 | Yes | ||
| 49 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 21823 | -3.268 | -0.1290 | Yes | ||
| 50 | ETS2 | 1416268_at 1437809_x_at 1447685_x_at | 21910 | -5.096 | 0.0011 | Yes |
